Amino acids and immune function
نویسندگان
چکیده
منابع مشابه
Functional Amino Acids and Intestinal Immune Function in Neonates
The gastrointestinal tract and the gut associated lymphoid system are critical to maintain both adequate nutrient absorption and defense against pathogenic microbes. In the piglet however, these systems are relatively immature at birth and develop over first six weeks of post-natal life. The introduction of early abrupt weaning places an enormous stress on piglets that is reflected in decreased...
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Aberrant alterations in glucose and lipid concentrations and their pathways of metabolism are a hallmark of diabetes. However, much less is known about alterations in concentrations of amino acids and their pathways of metabolism in diabetes. In this review we have attempted to highlight, integrate and discuss common alterations in amino acid metabolism in a wide variety of cells and tissues an...
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Wilms tumor protein (WT1) is a transcription factor selectively overexpressed in leukemias and cancers; clinical trials are underway that use altered WT1 peptide sequences as vaccines. Here we report a strategy to study peptide-MHC interactions by incorporating non-natural and photo-reactive amino acids into the sequence of WT1 peptides. Thirteen WT1 peptides sequences were synthesized with che...
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This paper addresses the classification task of data mining (a form of supervised learning) in the context of an important bioinformatics problem, namely the prediction of protein functions. This problem is cast as a hierarchical classification problem. The protein functions to be predicted correspond to classes that are arranged in a hierarchical structure (this takes the form of a class tree)...
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Amino acids regulate signalling through the mTORC1 (mammalian target of rapamycin, complex 1) and thereby control a number of components of the translational machinery, including initiation and elongation factors. mTORC1 also positively regulates other anabolic processes, in particular ribosome biogenesis. The most effective single amino acid is leucine. A key issue is how intracellular amino a...
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ژورنال
عنوان ژورنال: British Journal of Nutrition
سال: 2007
ISSN: 0007-1145,1475-2662
DOI: 10.1017/s000711450769936x